|
rs121913500
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study demonstrates that IDH1 R132H mutation with increased oncometabolite R-2HG in PCa cells may play important roles to increase PCa cell invasion.
|
31846689 |
2020 |
|
rs772893086
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study demonstrates that IDH1 R132H mutation with increased oncometabolite R-2HG in PCa cells may play important roles to increase PCa cell invasion.
|
31846689 |
2020 |
|
rs3181082
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicated that <i>CD1B</i> rs3181082 confers prostate cancer progression and may help improve clinical prognostic stratification.
|
31783478 |
2019 |
|
rs10993994
|
|
|
0.800 |
GeneticVariation |
BEFREE |
This study demonstrated a significant association between the MSMB rs10993994 polymorphisms and PCa risk.
|
31773691 |
2019 |
|
rs2297441
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>RTEL1</i> rs2297441 [odds ratio (OR): 1.23; 95% confidence interval (CI): 1.03-1.46, <i>P</i> = 0.021] and rs3208008 (OR: 1.23; 95% CI: 1.03-1.46) were associated with PCa risk.
|
31762827 |
2019 |
|
rs3208008
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>RTEL1</i> rs2297441 [odds ratio (OR): 1.23; 95% confidence interval (CI): 1.03-1.46, <i>P</i> = 0.021] and rs3208008 (OR: 1.23; 95% CI: 1.03-1.46) were associated with PCa risk.
|
31762827 |
2019 |
|
rs4073
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The major findings of this meta-analysis suggested that IL-8 rs4073 polymorphism is significantly associated with risk of prostate cancer.
|
31718853 |
2019 |
|
rs486907
|
|
|
0.100 |
GeneticVariation |
BEFREE |
CONCLUSIONS We report the effect of rs627928 on the development of prostate cancer and confirm that rs486907 is not involved in the risk of prostate cancer in the current meta-analysis.
|
31686670 |
2019 |
|
rs627928
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Nevertheless, rs627928 was reported to promote the development of prostate cancer (T vs. G: OR=1.08, 95% CI=1.01-1.15; TT+TG vs. GG: OR=1.14, 95% CI=1.03-1.25) in allele and recessive models in overall populations.
|
31686670 |
2019 |
|
rs145204276
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We aimed to investigate the effect of variant rs145204276 of GAS5 on the prostate cancer susceptibility and clinicopathologic characteristics.
|
31673232 |
2019 |
|
rs851023
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The MAPK14 gene SNP rs851023 was associated with PCa and aggressive PCa risk after multiple comparison adjustment.
|
31667711 |
2019 |
|
rs13426236
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study provides strong evidence showing that prostate cancer risk SNP rs13426236 upregulates expression of MLPH transcript V4, which may function as a candidate oncogene in prostate cancer.
|
31659808 |
2020 |
|
rs662
|
|
|
0.020 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b> We reported by the first time a correlation between rs662 (PON1) and PCa aggressiveness.
|
31647334 |
2019 |
|
rs35672330
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found two other EXO5 SNPs significantly associated with risk of PCa in cases-controls study from databases of genotype and phenotype (dbGaP), which are in linkage disequilibrium (D' = 1) with Exo5 L151P found in PCa family.
|
31616062 |
2020 |
|
rs919467999
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found two other EXO5 SNPs significantly associated with risk of PCa in cases-controls study from databases of genotype and phenotype (dbGaP), which are in linkage disequilibrium (D' = 1) with Exo5 L151P found in PCa family.
|
31616062 |
2020 |
|
rs1125927
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found 12 novel loci for PCa including rs1125927 (TMEM17, P = 3.95 × 10<sup>-16</sup>), rs73862213 (GATA2, P = 5.87 × 10<sup>-23</sup>), rs77911174 (ZMIZ1, P = 5.28 × 10<sup>-20</sup>), and rs138708 (SUN2, P = 1.13 × 10<sup>-15</sup>), seven of which had crucially low minor allele frequency in European population.
|
31562322 |
2019 |
|
rs138708
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found 12 novel loci for PCa including rs1125927 (TMEM17, P = 3.95 × 10<sup>-16</sup>), rs73862213 (GATA2, P = 5.87 × 10<sup>-23</sup>), rs77911174 (ZMIZ1, P = 5.28 × 10<sup>-20</sup>), and rs138708 (SUN2, P = 1.13 × 10<sup>-15</sup>), seven of which had crucially low minor allele frequency in European population.
|
31562322 |
2019 |
|
rs73862213
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found 12 novel loci for PCa including rs1125927 (TMEM17, P = 3.95 × 10<sup>-16</sup>), rs73862213 (GATA2, P = 5.87 × 10<sup>-23</sup>), rs77911174 (ZMIZ1, P = 5.28 × 10<sup>-20</sup>), and rs138708 (SUN2, P = 1.13 × 10<sup>-15</sup>), seven of which had crucially low minor allele frequency in European population.
|
31562322 |
2019 |
|
rs77911174
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found 12 novel loci for PCa including rs1125927 (TMEM17, P = 3.95 × 10<sup>-16</sup>), rs73862213 (GATA2, P = 5.87 × 10<sup>-23</sup>), rs77911174 (ZMIZ1, P = 5.28 × 10<sup>-20</sup>), and rs138708 (SUN2, P = 1.13 × 10<sup>-15</sup>), seven of which had crucially low minor allele frequency in European population.
|
31562322 |
2019 |
|
rs854560
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Moreover, in the stratified analyses by cancer type, polymorphism of PON1-L55M played a risk factor in the occurrence of breast cancer, hematologic cancer, and prostate cancer.
|
31467900 |
2019 |
|
rs4588
|
|
|
0.020 |
GeneticVariation |
BEFREE |
When studies were stratified by cancer type, our results indicated that rs4588 significantly increased the risk of breast cancer and digestive system tumor, but not in prostate cancer and non-small cell lung cancer, while rs7041 significantly increased the risk of non-small cell lung cancer.
|
31467173 |
2019 |
|
rs4938723
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Since miRNA-based mechanisms are shown to be involved in the pathogenesis of prostate cancer (PCa), the aim of the present study was to evaluate the effect of rs4938723, rs1076064 and rs4705343 occurring in regulatory regions of miR-34b/c, miR-143/145 and miR-378, respectively, on PCa risk and progression in Serbian population.
|
31423132 |
2019 |
|
rs1076064
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Since miRNA-based mechanisms are shown to be involved in the pathogenesis of prostate cancer (PCa), the aim of the present study was to evaluate the effect of rs4938723, rs1076064 and rs4705343 occurring in regulatory regions of miR-34b/c, miR-143/145 and miR-378, respectively, on PCa risk and progression in Serbian population.
|
31423132 |
2019 |
|
rs4705343
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Since miRNA-based mechanisms are shown to be involved in the pathogenesis of prostate cancer (PCa), the aim of the present study was to evaluate the effect of rs4938723, rs1076064 and rs4705343 occurring in regulatory regions of miR-34b/c, miR-143/145 and miR-378, respectively, on PCa risk and progression in Serbian population.
|
31423132 |
2019 |
|
rs1805794
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Recently, it has been reported that the pathogenicity of this mutation with regard to prostate cancer risk is modified by a missense variant of the same gene (E185Q).
|
31410679 |
2019 |